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Racellular functions such as protease cascades, extracellular morphogenetic peptides and secondary metabolism (Akanuma et al., 2009; Chater et al., 2010; Higo et al., 2012), but also contributing to the regulation of DnaA-mediated chromosome replication initiation (Wolanski et al., 2012). In S. griseus, many hundreds of direct targets for AdpA have been defined, and it is suspected that the unusua

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